Our skin is our largest organ and absorbs whatever we slather onto it and our underarms, in particular, are a sensitive area full of nodes, glands, and arteries. So, when it comes to the antiperspirant or deodorant we use every day, we want to make sure every ingredient is non-toxic.
The problem is that regulation of toxic ingredients used in personal care products in the US is practically non-existent. Many deodorants and antiperspirants available today contain ingredients that are proven or thought to be harmful to human health. Even worse, some ingredients either don't have any safety data available or have never been tested for toxicity.
Both Canada and the European Union have banned or restricted hundreds of ingredients from use in personal care products because of specific hazards like cancer, developmental toxicity and hormone disruption. However as US consumers, we have to be extra vigilant to protect our exposure.